Immunohistochemical examination
of HSP expression in mouse periodontal ligament cells due to mechanical stress
Rina Muraoka*,**，Takehiro Watanabe*,**，Keisuke Nakano*,***，Norimasa Okafuji*，
Saburo Kurihara***，Kazuhiro Yamada*,**，Toshiyuki Kawakami*,***
Matsumoto Dental
University Institute for Oral Science***
In course of orthodontic treatment, HSP
expression may caused by mechanical stress. We examined the profile change of
HSP immunohistochemically. Using male ddY mice, the Waldo method was applied. In the control
group, periodontal ligament was observed as physiological arrangement, which
weakly reacted to HSP27. In the experimental group the extension of the
periodontal ligament cells and the expansion of the blood vessel occurred in
the traction side. These tissues were strongly reacted to HSP27. These results
suggest that the role of the HSP expression was maintenance of the constancy of
the periodontal ligament cells.