Effect
of several bone-related drugs on the recovery of alveolar bone loss induced in
the experimental periodontitis in rats and hamsters.
Toshihiko Nagata
Department of Periodontology and Endodontology,
Periodontitis
is a chronic inflammatory disease caused by the infection of periodontopathic bacteriae. It clinically shows alveolar bone resorption, abscess formation, tooth mobility, and finally
tooth loss. To determine the
pathogenesis and to develop the prevention and treatment of periodontitis,
it is important to establish animal models of periodontitis. In this section, I show the effect of
several bone-related drugs (bisphosphonate, statin, PTH, and prostaglandin E2) on the recovery of
alveolar bone loss which is induced in experimental periodontitis
in rats and hamsters.