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Regeneration induction therapy based on DDS technology of growth factors

Masaya Yamamoto and Yasuhiko Tabata

Department of Biomaterials, Institute for Frontier Medical Sciences, Kyoto University

Tissue engineering is a newly emerging biomedical form to create a local environment which enables cells to promote the proliferation and differentiation for induction of tissue regeneration. The regeneration and repairing of tissues and organs have been achieved by making use of tissue engineering technology or methodology in a surgical or internally medical manner. For successful growth factor-induced tissue regeneration, it is important to develop drug delivery system (DDS) which can efficiently deliver the factor to the target site at the right concentration and the right timing over an appropriate time period. This paper overviews the recent development of growth factor delivery technologies necessary to realize the induction therapy of tissue regeneration.